Treatment of Brucella Abortus Infection
نویسندگان
چکیده
منابع مشابه
Brucella abortus infection acquired in microbiology laboratories.
We report an outbreak of laboratory-acquired Brucella abortus infection originating in the accidental breakage of a centrifuge tube. A total of 12 laboratory workers were infected (attack rate of 31%), with an incubation time ranging from 6 weeks to 5 months. Antibody titers were evaluated weekly in all personnel exposed, allowing the diagnosis of the infection in most cases before the onset of...
متن کاملA Case of Brucella Abortus Infection Treated with Prontosil
Previous history.?Nil. Recent movements.?Nil. Present in the regiment for more than the last year. Course of disease.?Duration of pyrexia was 140 days, It was continuous for the first 50 days with a double rise eveiy day. The temperature touched normal on the 51st day but became continuous for the succeeding four days after which it became intermittent. Temperature ranged from a minimum of 98.8...
متن کاملProtective effects of recombinant Brucella abortus Omp28 against infection with a virulent strain of Brucella abortus 544 in mice
The outer membrane proteins (OMPs) of Brucella (B.) abortus have been extensively studied, but their immunogenicity and protective ability against B. abortus infection are still unclear. In the present study, B. abortus Omp28, a group 3 antigen, was amplified by PCR and cloned into a maltose fusion protein expression system. Recombinant Omp28 (rOmp28) was expressed in Escherichia coli and was t...
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In this study, the Brucella abortus ohr gene coding for an organic hydroperoxide resistance protein (Ohr) was cloned into a maltose fusion protein expression system (pMAL), inserted into Escherichia coli, and purified, and its immunogenicity was evaluated by western blot analysis using Brucella-positive mouse sera. The purified recombinant Ohr (rOhr) was treated with adjuvant and injected intra...
متن کاملBrucella abortus genes identified following constitutive growth and macrophage infection.
The chronicity of Brucella abortus infection in humans and animals depends on the organism's ability to escape host defenses by gaining entry and surviving inside the macrophage. Although no human vaccine exists for Brucella, vaccine development in other bacteria has been based on deletions of selective nutritional as well as regulatory systems. Our goal is to develop a vaccine for Brucella. To...
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ژورنال
عنوان ژورنال: BMJ
سال: 1938
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.4060.884